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Winner Announced
We will be sending the prize for the November contest to Dr. Manoj Jain in Chandigarh, India. Read about the differential diagnoses Dr. Jain considered.did

November 2000 Answer

Prepared by:
Kyoung-Sik Cho, M.D.

Clinical History:
A 33-year-old female patient transferred for the further evaluation of a renal mass with a one month history of right flank pain.



Click to Enlarge
Figure 1a


Click to Enlarge
Figure 1b


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Figure 1c

Radiographic Findings:

Non-enhanced CT (Fig 1a) shows a round mass in the upper pole of the right kidney (arrows). CT number of the mass (40 HU) is slightly higher than renal parenchyma (30 HU). The mass shows homogeneous enhancement (66 HU) in the arterial phase (Fig 1b) and progressive enhancement (103 HU) in the delayed phase (Fig 1c).

Discussion:

Radiologic Differential Diagnosis

  1. Renal cell carcinoma.
  2. Benign renal tumor such as an angiomyolipoma.
Click to Enlarge

Renal adenoma is an uncommon benign renal tumor. It has been described in the pathology literature as a solid mass of variable size, occurring more commonly in young women, and sometimes associated with polycythemia (1). There is a debate over its benign or malignant nature. Some classify adenomas as adenocarcinoma if the diameter is larger than 3 cm, even though the cells are benign and identical in all respects to those of smaller lesions (2). Due to the broad range of biological behaviors seen in lesions assigned a microscopic diagnosis of adenoma, many pathologists classify all of renal adenoma as low-grade adenocarcinoma. The radiological literature has postulated that metanephric adenoma has high attenuation relative to the adjacent renal parenchyma on unenhanced CT because of psammomatous calcification and shows some enhancement and lower attenuation compared with the adjacent parenchyma on enhanced CT (2).

Diagnosis:

References:

  1. Davidson AJ, Hartman DS, Choyke PL, Wagner BJ. Diagnostic set: large, unifocal, unilateral. In: Radiology of the kidney and genitourinary tract. 3rd ed. Philadelphia, Saunders, 1999:269-270.
  2. Fielding JR, Visweswaran A, Silverman SG, Granter SR, Renshaw AA. CT and ultrasound features of metanephric adenoma in adults with pathologic correlation. J Comput Assist Tomogr 1999;23:441-444.
 
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