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	Over the last few years (see Radiology 4/98 and AJR 10/99) research has been published suggesting that screening ultrasound is useful as an adjunct to screening mammography in patients with dense breasts, even in patients with no specific mammographic findings. Weighing the increased time and expense needed against the increased yield of non-palpable, mammographically occult cancers found, is this a reasonable approach? Has it become the standard of care or will it soon become the standardof care?
	Answer provided by Dr.Ellen Shaw de Paredes: Screening ultrasound has certainly not become the standard of care in breast imaging and is unlikely to become so in the near future. Although there is some recent evidence that ultrasound in assymptomatic women with dense breasts may find some non-palpable occult cancers not seen on mammography, there is no consensus of opinion on this subject. Additional studies are needed to prove or disprove this concept. Package insert says that there's essentially no contraindications for Bracco ISOVUE use and pregnant females if the study is clinically indicated. Do you have information about fetal uptake of the contrastagent?