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This is a gross colectomy specimen of a
patient with ulcerative colitis. The different stages and extent of
this pancolitis are nicely demonstrated with areas of red, hemorrhagic,
and inflamed mucosa transitioning into areas of extensive ulceration
and pseudopolyp formation (these are islands of remaining mucosa surrounded
by a sea of ulceration). Colectomy is the treatment of choice for
patients with extensive disease (15% to 25% of patients). |