Talking points

 Talking points

• Warming wounds  
• Timely diagnosis of rabies  
• Childhood abuse and depression in women  
• You're only as healthy as your thyroid  
• No benefit from interferon alpha-2a  

Original research

 Articles

• Prediction of all-cause and cardiovascular mortality in elderly people from one low serum thyrotropin result: a 10-year cohort study James V Parle, Patrick Maisonneuve, Michael C Sheppard, Peter Boyle, Jayne A Franklyn
• Effect of long-term adjuvant therapy with interferon alpha-2a in patients with regional node metastases from cutaneous melanoma: a randomised trial Natale Cascinelli, Filiberto Belli, Rona M MacKie, Mario Santinami, Rosaria Bufalino, Alberto Morabito
• Effect of arterial revascularisation on survival: a systematic review of studies comparing bilateral and single internal mammary arteries David P Taggart, Roberto D'Amico, Douglas G Altman
• Effects of preoperative warming on the incidence of wound infection after clean surgery: a randomised controlled trial Andrew C Melling, Baqar Ali, Eileen M Scott, David J Leaper
• Adult onset of major depressive disorder in relation to early life violent victimisation: a case-control study Lauren A Wise, Sally Zierler, Nancy Krieger, Bernard L Harlow

 Case report

• Cure of lifelong fatigue by calcium supplementation Dominik Mark Alscher, Thomas Mettang, Ulrich Kuhlmann

 Research letters

• Uptake of screening and prevention in women at very high risk of breast cancer D G R Evans, F Lalloo, A Shenton, C Boggis, A Howell
• Application of a molecular marker for surveillance of chloroquine-resistant falciparum malaria Abdoulaye Djimdé, Ogobara K Doumbo, Richard W Steketee, Christopher V Plowe
• Nucleic-acid sequence based amplification in the rapid diagnosis of rabies Supaporn Wacharapluesadee, Thiravat Hemachudha
• Metformin in non-alcoholic steatohepatitis Giulio Marchesini, Mara Brizi, Giampaolo Bianchi, Sara Tomassetti, Marco Zoli, Nazario Melchionda

News

 Science and medicine

• US biological defence research under the spotlight Haroon Ashraf
• Mutation predicts relapse in acute myeloid leukaemia Marilynn Larkin
• Obesity and diabetes epidemics show no sign of abating Helen Frankish
• S-nitrosothiols--lots of deep breaths required James Butcher
• How cooling might help MS symptoms Rebecca Love

News in brief  

 Feature

• Artificial intelligence slips cautiously into the clinic Marilynn Larkin

 Dispatches

• WASHINGTON Bush stem-cell plans draw scepticism in Senate Daniel S Greenberg

 Policy and people

• Heads of state meet to plan "a world fit for children" Faith McLellan
• UK nurses receive guidance on covert medication of patients Sarah Ramsay
• Indian government's first update of national health policy in 18 years Sanjay Kumar
• European parliament revises blood donation legislation Karen Birchard
• Health ministers of south east Europe agree to cooperate to improve health Ana Marusic

News in brief  

• UN agency urges control for drug domain names Clare Kapp

Editorial and review

• Recruitment of women to clinical trials The Lancet

 Commentary

• Sponsorship, authorship, and accountability Frank Davidoff, Catherine D DeAngelis, Jeffrey M Drazen, John Hoey, Lisselotte Højgaard, Richard Horton, Sheldon Kotzin, M Gary Nicholls, Magne Nylenna, A John P M Overbeke, Harold C Sox, Martin B Van Der Weyden, Michael S Wilkes
• Adverse effects of subclinical hyperthyroidism Vahab Fatourechi
• Role of melanocortins in control of obesity Brent E Wisse, *Michael W Schwartz
• Pathways of progression in hepatocarcinogenesis Henry C Pitot

 Review

• Rheumatoid arthritis David M Lee, Michael E Weinblatt

 Viewpoint

• Private practitioners and public health: weak links in tuberculosis control Mukund Uplekar, Vikram Pathania, Mario Raviglione

 Eponym

• Goodpasture's disease Alan D Salama, Jeremy B Levy, Liz Lightstone, Charles D Pusey

 Uses of error

• Uses of error: Surgical mistakes Shehan Hettiaratchy

Correspondence

 Correspondence

• Researcher, clinician, or teacher? J E Banatvala
• Missing HIV kits in Pakistan Athar Saeed Dil
• Global tobacco control Larry Norton, Paul Bunn
• Integrity in Science Database Ronald Collins
• Poisson distribution to assess actinic keratoses in xeroderma pigmentosum Peter Lachenbruch, Louis Marzella, William Schwieterman, Karen Weiss, Jay Siegel
• Outcome in anorexia nervosa Janice Russell, Suzanne Abraham, Stephan Zipfel, Wolfgang Herzog
• Fetal origins hypothesis in India Patrick J Bradley
• A non-sense mutation and protection from severe malaria Felix I D Konotey-Ahulu
• Effective provision of antenatal care Wendy Holmes
• Countries' health performance Joshua Cohen
• It could only happen to a vet John H Taylor
• Another sniffer dog for the clinic? John Church, Hywel Williams
• Standard methods to measure HIV drug concentrations Andrew D Luber, Concepta Merry

Clinical picture

 Clinical picture

• Clinical picture: Subphrenic abscess and rupture of the spleen Alexander Woywodt, Jan Thomas Kielstein, Michael Winkler

Dissecting room

 Media reviews

• Managing end-stage renal disease: an ethical arena John B Dossetor
• The dazzling collections of Catherine the Great Christopher Cundy
• Jocks and Japanese collaborate David Jack
• Cardiac imaging John Bignall
• Second to none under the sun Colin Martin

 From the medical museum

• From the medical museum Ruth Richardson

 Art

• Celestial Treasury  

 Lifeline

• David Warrell  

 Jabs and jibes

• Health promotion Druin Burch